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Even though DNA self-assembly is achievable without any outside the house assistance making use of different substrates like provision of catatonic area of Aluminium foil, DNA ligase can offer the enzymatic help that is needed to make DNA lattice framework from DNA over hangs.[fifteen] Background[edit]
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It is much more steady and active at Extraordinary temperatures than standard DNA ligases. It's Employed in DNA amplification reactions to detect mutations in mammalian DNA.
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